台灣大學醫學系畢業後，返回新港鄉執業。因不願見到鄉親沉淪「大家樂」賭博行為，邀雲門舞集林懷民率團回鄉公演，並創辦新港文教基金會，以教育、文化新思維，讓新港鄉成為台灣社區營造的典範。40多年來，陳錦煌除了治病，並營造健康社區環境不遺餘力，開立「社會處方箋」，溫暖解決社會的病痛。
出身於軍人家庭，就讀國防醫學院時，就開始省下自己的零用錢來資助貧童。在佳里創辦以琳內科診所，讓鎮民不需再大老遠跋涉到台南市區洗腎。他又成立以琳之家急難救助中心，為弱勢家庭的學生們打造另一個「家」，讓孩子不再孤立無援。
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